MGR1 and MGR2

MGR1, a probe that is cell permeable and generates reactive oxygen species within cells has been developed by Prof Harinath Chakrapani's lab. This probe was recently listed in Merck's website:

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References: 1. Dharamaraja, A. T; Alvala, M.; Sriram, D.; Yogeeswari, P.; Chakrapani, H. Chemical Communications, 2012, 48, 10325-10327. 2. Dharamaraja, A. T; Chakrapani, H. “A Small Molecule for Controlled Generation of Reactive Oxygen Species (ROS)” Organic Letters, 2014, 16, 398-401. 3. Kelkar, D.; Ravikumar, G; Mehendale, N.; Singh, S.; Joshi, A.; Sharma, A. K.; Mhetre, A.; Rajendran, A.; Chakrapani, H.; Kamat, S. S. “A chemical–genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase” Nature Chemical Biology, 2019, 15, 169-178.

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